Be Vibrant, Be Vital with Primeadine®

The purest plant-based spermidine supplement, derived from Japan. Slow aging at a cellular level for a healthier, more vibrant you.

Unlock Radiant Wellness

Primeadine® is a comprehensive longevity tool, elevating spermidine levels to support cellular renewal and combat the root causes of aging. As spermidine production declines with age, Primeadine® helps your body restore its natural balance and vitality.

View all

Real People, Real Results

Welcome to Your New Prime

Aging isn't just about adding years to life—it's about adding life to your years. Experience newfound vitality, wellness, and vibrancy.

Restore Balance

Target aging from within by reducing inflammation, regenerating stem cells and mitochondria, and activating cell renewal. This reflects inside and out with elevated energy levels, a radiant glow, and deeper, more restful sleep.

Support Sleep

Harmonize with your body's natural sleep cycle for a night of profound rest. Awaken fully recharged, with the vitality to face whatever your day holds.

Boost Hair, Skin & Nails

Promotes hair follicles' transition from the shedding to growth phase and supports collagen synthesis. Clients report enhanced hair growth, fuller lashes and brows, and healthier skin and nails.

Recommended by Experts

Dr. Olivia Lesslar

@drolivialesslar

Medical Doctor with a Special Interest in Longevity & Complex Conditions

Primeadine is an exceptional quality spermidine that I use in many protocols, especially when I am trying to induce autophagy. These include such diverse protocols as those for tinnitus, post-viral syndromes, 'autoimmunity', and graying hair! I am especially pleased to have a gluten-free version to offer patients. 

Nadine Artemis

@nadineartemisofficial

Beauty Philosophist, Author & Founder of Living Libations

My renegade beauty secret for deeper sleep, stronger nails, longer lashes, fuller hair, smoother skin, and fading freckles.

Dr. Sandra Kaufmann

@kaufmannantiaging

"Best in Medicine" Longevity Doctor & Author of The Kaufmann Protocol: Why We Age and How to Stop It

There is no question that spermidine is a crucial component to any longevity program. Thankfully, Oxford Healthspan offers an unparalleled product line. The quality is unprecedented, derived from naturally-sourced materials and manufactured in Japan. The products contain not only spermidine, but related polyamines which provide additional health benefits. I highly recommend this product line to all of my patients.

Carol Vorderman

@carolvorders

British TV personality & Biohacker

I’m nearly 62, and I started looking into lowering my biological age. Primeadine supplements really help with, fundamentally, what’s called autophagy, which is getting rid of rubbish in your cells and using it for energy and for cell renewal and for your brain as well. Lots of you ask about what I take and this is a key essential.

Luke Storey

@lukestorey

Writer, Meditation & Metaphysics Teacher & Lifestyle Design Expert

The best spermidine supplement on the market.

Magdalena Groselj

@magdalenas_secrets

Biohacker & Anti-Aging Entrepreneur

I’ve noticed (via the Oura ring app) my deep and REM sleep improved enormously! My nails are so firm and my skin is even more beautiful and glowing. If you want to improve your health and rejuvenate your body, I suggest following an anti-aging protocol with Primeadine.

Dr. Stephanie Estima

@dr.stephanie.estima

Women’s Health Expert & Author of “The Betty Body”

My hair was starting to go from gray back to […] dark brown. It was gray, and now it’s back to its original color. When I think about spermidine as a whole, the way I am viewing it is as a way to reduce systemic inflammation.

Zora Benhamou

@hackmyage

Gerontologist, Biohacker & Sports Nutrition Coach

I’ve been taking Primeadine spermidine on and off for about 3 years. Every time I go on it, my sleep or recovery scores on my tracking devices go up. And when I go off of it, after several weeks they start to drop.

Nathalie Niddam | Oxford Healthspan

Nathalie Niddam

@nathalieniddam

Certified Holistic Health Coach & Biohacker

Primeadine upregulates autophagy and mitophagy, helps the immune system to rejuvenate plus it protects DNA and supports deep sleep, hair skin, and nails. It’s a staple in my supplement stack!

One of my non-negotiable supplements for better skin, hair, lash growth, and autophagy. And best of all - improved sleep.

Dr. Olli Sovijarvi

@ollisovijarvi

Pioneer of Holistic & Preventive Medicine in Finland & Medical Doctor & CEO of Biohacking Center

My wife has been taking it for six months and I think she looks younger and her hair growth has come back after pregnancy, and nails, and all kinds of things that are a reflection of good vitality.

The top longevity supplement for gray hair, hair loss, and anti-aging. I've been taking this for two months and I've already noticed less hair shedding. Eyelashes look longer and stronger, my skin is brighter and I'm getting much more deep sleep.

Image of Leslie Kenny

Our Founder: Leslie Kenny

When Leslie was 37 she was diagnosed with a trio of autoimmune diseases - lupus, rheumatoid arthritis, and Hashimoto's Thyroiditis - and told she had five years to live. Now, in her late 50’s, she is autoimmune disease-free, has no gray hair, and is biologically 21.

Read more