The Science & Art of Aging Well

Autophagy Image shows a cell with mitochondria | Oxford Healthspan.
Autophagy

Disabled Macroautophagy: Hallmark of Aging #10

Macroautophagy is one type of autophagy and involves the containment of cytoplasmic material into vesicles, whose contents are later digested or broken down into parts by lysosomes, another cellula...

Hallmarks Of AgingAltered Intracellular Communication: Hallmark of Aging #9

Altered Intercellular Communication: Hallmark of Aging #9

As people (and their cells) age, the communication between their cells change. Although the cells aren’t deciding not to communicate, the communication becomes deregulated particularly as inflammat...

BeautyStem Cell Exhaustion: Hallmark of Aging #8

Stem Cell Exhaustion: Hallmark of Aging #8

The latest anti-aging skincare product might promise to repair, renew, and rejuvenate, however, they don’t promise to regrow. Only your stem cells can do that; but this is actually what you need most.

EnergyMitochondrial Dysfunction: Hallmark of Aging #6 | Oxford Healthspan

Mitochondrial Dysfunction: Hallmark of Aging #6

We’ve made it to the 6th of the 12 hallmarks of aging: mitochondrial dysfunction! Mitochondrial dysfunction is part of the antagonistic group of hallmarks. 

Hallmarks Of AgingLoss of Proteostasis: Hallmark of Aging #4 | Oxford Healthspan

Loss of Proteostasis: Hallmark of Aging #4

To function, proteins need to be folded perfectly. And, for our bodies to function, we need this process to be conserved and protected: Proteins are responsible for nearly every task in our body in...

Hallmarks Of AgingTelomere Attrition: Hallmark of Aging #2 | Oxford Healthspan

Telomere Attrition: Hallmark of Aging #2

In the last blog post discussing Hallmark #1, we talked a lot about how DNA damage accompanies aging. A particular brand of DNA damage is telomere attrition or loss, the second hallmark.