With respect to food sources, spermidine is found in the greatest amounts in wheat germ and fermented soy (e.g. natto and tempe). Wheat germ-derived, in particular, has a very high spermidine content and the wheat germ in Primeadine® has a beneficial ratio of spermidine to the other polyamines, spermine and putrescine. Wheat germ derived spermidine is also well absorbed in the GI tract due to its high molecular mass.
What customers are saying
I’ve been taking Primeadine for the past 5 months and my doctor tells me I’m in a great shape. I feel better and stronger.
Sir Christopher Ball, Guinness World Record Holder
(10 marathons in 10 days)
My nails are definitely in better condition and so is my sleep quality! I seem to have less
hair loss too.
Pauline, retired teacher
I'm close to 30 days into Primadine®. Deep sleep is clear and has increased from day 1 (if taken at night). I'm also averaging 7 hours a night which is unheard of for me.
Tim Kane, CEO myHSA
I've been taking Primeadine for 5 months, and what I have noticed more than anything
is how great I'm sleeping. I am averaging 9 hours of sleep a night. I feel rested
throughout the day and have stayed healthy -- I haven't even had a cold since taking it.
After taking Primeadine® for 2 months, I've noticed brighter skin tone, thicker hair (less
hair loss) and, according to my Oura ring data, increased deep sleep.
Since taking Primeadine® 2 1/2 months ago, I have seen two incredible benefits.
My hair loss has stopped and my hair is growing thicker in places where it was previously thin. My ability to lose weight has also been enhanced, allowing me to move past a plateau I always hit: I've now lost 10 pounds since taking the product!
I've had a big increase in my HRV since taking Primeadine. It's normally low (18-20 as per Oura ring), and I've nearly doubled my average (up to 40). It also appears to be having a stomach flattening effect. Will definitely continue with it.
I have had more hair growth in areas where I hadn’t seen it in years and I noticed that the ridges in my nails had completely disappeared!
Spermidine is a cornerstone in Japan's aging wisdom, known for boosting autophagy which is the body's cellular renewal and recyclingprocess that slows as we age.
Aging might be a natural process but that doesn't mean you can't do anything about it. Spermidine works to support brain and heart health. It also helps with age-associated sleep disruption. Japanese centenarians on the island of Okinawa consume a spermidine-rich diet.
Thought your prime was over? Welcome to the new prime of life. Spermidine improves hair growth and fullness (including eyelashes) and strengthens nails.
Primeadine® is the purest spermidine supplement on the market, with zero fillers or flow agents.
Our formulation provides you with 1mg standardised spermidine, tested in every batch to guarantee you are getting the same amount in every capsule.
To prevent oxidation and the presence of potentially rancid omega 6’s, our wheat germ extract is defatted and, again, tested for purity and potency.
We have also added a special type of maltodextrin that is acting as a prebiotic fiber and resistant starch that will selectively feed the fuso- and bacterioides bacteria in the gut biome, both of which produce spermidine. The idea behind it is to increase both supplemental, exogenous spermidine as well as your own body's ability to produce endogenous spermidine.
Our Promise to you
We bridge the gap between eastern wisdom and modern science by bringing to market high quality, effective and science-backed botanical compounds, many from the Japanese Imperial Palace Medical Scrolls that harness the body’s innate ability to repair, renew and promote vigorous longevity and increased healthspan.
High Standards For Optimal Results
Meet our Founder
Leslie Kenny is an autoimmune disease survivor and certified health coach. After meeting world-class Oxford scientists with potentially life-changing discoveries, Leslie realised she was in a unique position to bring these discoveries to the consumer and share ancient wisdom, now backed by science, with the world. The question she is aiming to answer: if I was able to reverse my autoimmune diseases, can I reverse aging?
In response, Oxford Healthspan, Maker of Primeadine®, was born. She founded Oxford Healthspan to identify healthy aging compounds with strong clinical safety profiles and bring them to market as nutritional supplements. Primeadine® is the first product, a food-based, spermidine-rich supplement.
Getting started with Primeadine®
We answer your most common questions so that you can maximize the benefits from taking Primeadine® from Day 1.
Read about the myriad benefits of this potent polyamine, known for inducing autophagy, the body's cellular renewal and recycling process that slows as we age.
As featured in
Frequently Asked Questions
Stay in touch!
Be the first to hear about the latest research, new product developments and exclusive discounts. You'll also gain free access to our smart-aging webinars.