Aging, activated.
About Oxford Healthspan
We are a female-founded healthy aging brand, built on Oxford-led science and a radical belief: that the body, given the right support, is capable of far more than we've been told.
Everything we make is grounded in rigorous research, crafted with integrity, and designed to work with your body's innate wisdom, not override it.
The story behind the science
Meet Our Founder & CEO, Leslie Kenny
In her late 30s, Leslie Kenny was diagnosed with multiple autoimmune conditions and told her future would be limited. She chose to take a different approach.
Through nutrition, lifestyle, and a deepening interest in cellular health, Leslie began to support her body from within. She went on to collaborate with scientists, including researchers affiliated with the University of Oxford, to better understand the biology of aging and how to work with it. She also conceived naturally at age 43.
That journey became Oxford Healthspan: a mission to make carefully developed, science-led, food-derived supplements accessible to everyone who refuses to accept decline as inevitable.
A discovery hiding in plain sight
Why spermidine?
Spermidine is a naturally-occurring compound found in all living cells and in small amounts in certain foods. Leslie was introduced to it through her collaboration with Professor Katja Simon at the University of Oxford, at a time when it was largely confined to research settings.
It has since been studied for its association with autophagy, the body's natural cellular renewal process. As spermidine levels decline with age, so does the efficiency of that renewal. This area of research became a cornerstone of Oxford Healthspan.
Whole-food spermidine. Thoughtfully formulated.
What is Primeadine®?
Primeadine is a whole-food spermidine supplement designed to support cellular health, longevity, and overall vitality over time. It is built on a simple philosophy: work with the body's natural processes, prioritize quality and consistency, and focus on long-term nourishment, not short-term outcomes.
Every batch is carefully sourced from Japan and independently tested for purity and potency.
Today, Primeadine is part of the daily wellness practice of customers worldwide, each on their own journey toward a radiant, thriving life.
Science you can trust. Expertise you can verify.
Scientific & Clinical Advisory Board
Our work is guided by an international network of scientific and clinical advisors, many affiliated with the University of Oxford, spanning physiology, immunology, longevity science, and clinical nutrition.
Their involvement ensures that everything we do remains grounded in the latest research and scientific integrity, not in hype, trends, or empty promises.
Professor Denis Noble (University of Oxford)
Emeritus Professor of Physiology and pioneer in systems biology. Co-founder of the Oxford Longevity Project.
Dr. Ghada Alsaleh (University of Oxford)
Researcher in immunology and autophagy that leads the UK's first space innovation lab, with a focus on aging and immune function.
Dr. Katja Simon (Max Delbrück Center, Berlin)
Leads research into autophagy in the immune system, including its role in cellular maintenance.
Dr. Sasi Senga (University of Oxford)
Neurosurgical oncologist and researcher focused on cancer biology.
Dr. Olivia Lesslar (Global)
Celebrity longevity doctor specializing in complex chronic conditions and integrative approaches to health. Featured in NYC Journal's 50 under 50.
Dr. Sandra Kaufmann (Miami)
"Best in medicine" longevity doctor and researcher with a background in cellular biology and aging.
Dr. Paul Ch'en (University of Oxford)
University of Oxford college GP and co-founder of the Oxford Longevity Project, with interests in preventative and holistic care for cancer.
Amy Lamotte (Hong Kong)
Clinical nutritionist specializing in personalised nutrition and immune health.
Radiant wellness, thoughtfully earned
Our approach
We believe aging well should feel clear, grounded, and achievable. Not overwhelming. Not out of reach.
That means science thoughtfully applied, whole-food ingredients selected with care, and a focus on consistency over quick fixes. A considered approach, designed to support your health as part of a life well lived.