Primeadine Original and Primeadine GF are both wholly food-derived with the amount of spermidine, 1mg, that has been used in human clinical trials showing enhancement of memory and cognition.
Primeadine Original is derived from concentrated, defatted wheat germ and has a small amount (40mg) of gluten. We have been unable to recommend this to clients who are celiac or suffer from Small Intestinal Bacterial Overgrowth (SIBO) or Leaky Gut as a result.
Because we know that spermidine can be helpful to sealing the gut lining, we wanted to find a source of spermidine that would be suitable for these individuals.
Primeadine GF contains chlorella which is itself a good source of naturally occurring nutrients, including B vitamins such as folate and B12, as well as iron. These are all important nutrients for women of childbearing age. In addition, for those individuals who are unable to metabolize folic acid, this is a source of bioavailable folate.
Primeadine GF is a source of vitamins D and K, both of which are needed to drive calcium to the bones.
In addition, Primeadine GF contains nobiliten, a molecule shown to trigger autophagy and pairs nicely with spermidine. Because spermidine has natural anti-inflammatory properties, we wanted to enhance this even further by adding in some turmeric.
As a source of polyamines, Primeadine GF contains both spermidine and putrescine, a precursor to spermidine to help your body recycle and manufacture more of its own spermidine.
All our ingredients are sourced and manufactured on the Longevity Blue Zone of Okinawa in Japan in FDA registered facilities and to ISO22000 standards, the highest food grade manufacturing standards that exist.