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Oxford Healthspan

Primeadine Premium Spermidine Supplement

Rated 4.9 out of 5
Based on 42 reviews

📢 Interested in a 3 bottle bundle? Click here
    • Concentrated wheat germ extract containing 1mg of supplemental, exogenous spermidine. Defatted to prevent the oils in wheat germ from going rancid.
    • Maltodextrin (FOS/prebiotic): acts as a prebiotic fiber and resistant starch that will selectively feed the fuso- and bacterioides bacteria in your gut biome, both of which produce spermidine. This is to support your gut biome's own ability to produce its own spermidine.
    • Hypromellose (plant cellulose capsule). Vegan.
Japan Health and Nutrition Food Association JHNFA JHFA logo
Lab tested
No talc
No shellac

Benefits of our Spermidine Supplement

Beauty

Enhances hair growth and fullness, including eyelashes and eyebrows, and promotes nail growth and strength

Healthy aging

Supports memory, cognition and brain and cardiovascular health

Sleep

Assists with deeper, sounder sleep and circadian reset

Longevity

Boosts autophagy, which declines with age, and promotes cellular renewal

What is spermidine?

Spermidine is a potent polyamine, known for inducing autophagy, which is the body's cellular renewal and recycling process that slows as we age.

Supplementation with spermidine in humans has been shown to support cognition and heart health, promote hormonal balance and improve hair growth and fullness (including eyelashes and eyebrows), and strengthen nails.

Epidemiological studies have correlated higher spermidine levels with longer life.

The gut biome and our tissues produce 2/3 of our body's spermidine. This is known as 'endogenous production'. The final third comes 'exogenously' or externally from our diet.

As we age, spermidine production in our tissues and gut biome begins to fall, reducing autophagy, and therefore cell renewal.

Spermidine inhibits 6 of the 9 Hallmarks of Aging 

Hallmark of Ageing

average rating 4.9 out of 5
Based on 42 reviews
  • 5 Stars
    38 Reviews
  • 4 Stars
    2 Reviews
  • 3 Stars
    2 Reviews
  • 2 Stars
    0 Reviews
  • 1 Star
    0 Reviews
95% of reviewers would recommend this product to a friend
Customer photos and videos
42 Reviews
Reviewed by Mike
Verified Buyer
I recommend this product
Age Range
55 - 64
Gender
Male
Wellness Concern
  • Sleep
  • Cognition
  • Overall Health
  • Aging well
  • Aches & Pains of Aging
The Pros
  • Easy to use
  • Clean ingredients
  • Science behind the product
  • Positive results
  • Speed of action
Rated 5 out of 5
Review posted

Unexpected and Pleasant Surprise

I have been taking this for about 2 and a half months and am in love with it. I started taking it for cell autophagy after my trainer told me about spermadine, specifically recommending the one Primeadine makes because of the quality of their product.

The first thing I noticed was better sleep, almost right away. After about a month I could notice more natural energy. After about two months, I started to notice ( well, my wife noticed first) stronger erections. I didn’t have a problem with ED, but I am a 56 year old male. So naturally, things don’t work the same as when you are in your twenties. But recently have been starting to feel like I am. This supplement has been one of the best additions to my lifestyle.

I can’t wait to see what the next few months bring.

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Reviewed by Kaja T.
I recommend this product
Age Range
25 - 34
Gender
Female
Wellness Concern
  • Hair loss
  • Sleep
  • Energy levels
  • Overall Health
  • Skin Health
The Pros
  • Easy to use
  • Speed of action
  • Positive results
  • Science behind the product
Rated 5 out of 5
Review posted

The best supplement on the market!

This product helped me so much! I always had problems with falling asleep and since I am taking spermidine I fall asleep immediately and I feel rejuvenated in the morning. Also I had post Covid syndrome- my hair and nails were really in bad condition- spermidine helped me with that too. I just can’t thank it enough.

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Reviewed by Caroline B.
Verified Buyer
I recommend this product
Age Range
45 - 54
Gender
Female
Wellness Concern
  • Skin Health
  • Aging well
  • Hormonal Health
The Pros
  • Clean ingredients
  • Easy to use
  • Speed of action
  • Science behind the product
  • Positive results
Rated 5 out of 5
Review posted

Seems to be working! 46 and looking young

I’m on my third month and I feel like my skin is looking smooth and glowy. Been getting a lot of compliments on it and how few wrinkles I have (turning 47 this summer), so I’ll keep with it! Love this company.

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Reviewed by phil j.
Verified Buyer
I recommend this product
Age Range
65+
Gender
Male
Wellness Concern
  • Energy levels
  • Sleep
  • Overall Health
Rated 5 out of 5
Review posted

Spermidine is great

I have taken Spermidine for 4 months . I am going to stop for 2 months and start again

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Reviewed by JoAnna H.
Verified Buyer
I recommend this product
Age Range
35 - 44
Gender
Female
Wellness Concern
  • Skin Health
  • Aging well
  • Overall Health
The Pros
  • Easy to use
  • Speed of action
  • Positive results
Rated 5 out of 5
Review posted

Quick Results

I've only been taking the supplement for a few weeks. I wasn't expecting to really see any difference for at least a few months, but was pleasantly surprised that this wasn't the case. Within DAYS I saw an improvement in my skin. I have been struggling with breakout for months and almost immediately began to see improvements. I'm hoping to be one of those people who see their grey hair reversible! Stay tuned 🙂

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