Gluten-free spermidine just launched.

Buy Now

Search

Search

Free shipping on orders over $75. Applies at checkout!

Primeadine Premium Spermidine Supplement

Rated 4.7 out of 5
Based on 55 reviews

Interested in a 3 bottle bundle?  Click here
    • Concentrated wheat germ extract containing 1mg of supplemental, exogenous spermidine. Defatted to prevent the oils in wheat germ from going rancid.
    • Maltodextrin (FOS/prebiotic): acts as a prebiotic fiber and resistant starch that will selectively feed the fuso- and bacterioides bacteria in your gut biome, both of which produce spermidine. This is to support your gut biome's own ability to produce its own spermidine.
    • Hypromellose (plant cellulose capsule). Vegan.
GMP quality
Japan Health and Nutrition Food Association JHNFA JHFA logo
Lab tested
No talc
No shellac

Benefits of our Spermidine Supplement

Beauty

Enhances hair growth, fullness, shine and texture including eyelashes and eyebrows, and promotes nail growth and strength

Healthy aging

Supports memory, cognition and brain and cardiovascular health

Sleep

Assists with deeper, sounder sleep and circadian reset

Longevity

Boosts autophagy, which declines with age, and promotes cellular renewal

What is spermidine?

Spermidine is a potent polyamine, known for inducing autophagy, which is the body's cellular renewal and recycling process that slows as we age.

Supplementation with spermidine in humans has been shown to support cognition and heart health, promote hormonal balance and improve hair growth and fullness (including eyelashes and eyebrows), and strengthen nails.

Epidemiological studies have correlated higher spermidine levels with longer life.

The gut biome and our tissues produce 2/3 of our body's spermidine. This is known as 'endogenous production'. The final third comes 'exogenously' or externally from our diet.

As we age, spermidine production in our tissues and gut biome begins to fall, reducing autophagy, and therefore cell renewal.

Spermidine inhibits 6 of the 9 Hallmarks of Aging 

Hallmark of Ageing

average rating 4.7 out of 5
Based on 55 reviews
  • 5 Stars
    47 Reviews
  • 4 Stars
    3 Reviews
  • 3 Stars
    3 Reviews
  • 2 Stars
    1 Review
  • 1 Star
    1 Review
91% of reviewers would recommend this product to a friend
Customer photos and videos
55 Reviews
Reviewed by Emma C.
Verified Buyer
I recommend this product
Age Range
35 - 44
Gender
Female
Wellness Concern
  • Sleep
  • Energy levels
  • Overall Health
  • Skin Health
The Pros
  • Easy to use
  • Clean ingredients
  • Speed of action
  • Positive results
  • Science behind the product
Rated 5 out of 5
Review posted

My number one supplement

For me Primadine has been life changing. I have noticed my deep sleep has greatly improved and so has my digestion. It is the one supplement I will NEVER be without.

Loading...
Was this helpful?
Reviewed by Gina A.
Verified Buyer
I recommend this product
Age Range
45 - 54
Gender
Female
Wellness Concern
  • Hair loss
The Pros
  • Speed of action
  • Science behind the product
  • Positive results
  • Easy to use
  • Clean ingredients
Rated 5 out of 5
Review posted

Skeptical no more!

I originally bought one bottle after a friend recommended it for my Covid hair loss. After about three weeks I was noticing a big difference in the amount of hair I was losing every day so I bought a second bottle. Just finishing up the second bottle and I am now losing less hair on a daily basis than I did before I ever had Covid! My hair is starting to feel and look fuller and healthier. Very happy with the product!

Loading...
Was this helpful?
Reviewed by Mike F.
Verified Buyer
I recommend this product
Age Range
45 - 54
Gender
Male
Wellness Concern
  • Hair loss
  • Hormonal Health
  • Energy levels
  • Overall Health
  • Sleep
The Pros
  • Science behind the product
  • Positive results
Rated 5 out of 5
Review posted

Great results

I've been through the studies and I understand what results I may expect, of which most I cannot see or feel. That being said, the main indicator is new hair growth at my hairline over the past few months. I am not taking anything else for this, so I see it as an indication that this is working.

Loading...
Was this helpful?
Reviewed by Nick U.
Verified Reviewer
I recommend this product
Age Range
25 - 34
Gender
Male
Wellness Concern
  • Aging well
  • Overall Health
  • Cognition
  • Energy levels
The Pros
  • Clean ingredients
  • Science behind the product
Rated 5 out of 5
Review posted

Awesome product

I researched all the spermidine products on the market and am most impressed with Primeadine. It contains the appropriate dose used in clinicial trials and also stimulates the body’s natural spermidine production. I’m young, but it has quickly earned a spot in my longevity protocol. Leslie Kenny, the Founder of Oxford Healthspan is a gem! Thank you.

Loading...
Was this helpful?
Reviewed by Kim J.
Verified Buyer
I don't recommend this product
Age Range
45 - 54
Gender
Female
Wellness Concern
  • Hormonal Health
  • Skin Health
  • Energy levels
  • Hair loss
  • Sleep
The Pros
  • Easy to use
Rated 2 out of 5
Review posted

1 month

I have not noticed anything yet, not sure if it takes more than a month to see any results.

Loading...
Was this helpful?