Add to room temperature drinks or food
Comes with traditional Japanese wild cherry tree bark storage box, the "Kiseki"
Easy to integrate into your routine
ISO22000 standard, the highest in food quality control
Made from concentrated & defatted Japanese wheat germ extract
Each serving provides 1mg plant-derived spermidine

Primeadine® Original Spermidine Powder Luxury Starter Kit - 3-Month Supply

Sale price£250.00
Sale price Regular price£250.00

Primeadine® Original spermidine powder makes it easier than ever to activate cell renewal and promote longevity.

Included in the Luxury Starter Kit:

  • 3-Month Supply Powder Pouch
  • Hand-crafted Japanese storage box, the "Kiseki"
  • Recipe Booklet
  • Comes in a beautiful, premium box, making an ideal gift for yourself or a loved one.

Please note, this product is non-refundable.

American Express Apple Pay Diners ClubDiscoverMeta Pay Google Pay MastercardPayPalShop Pay Venmo Visa

Please view our Shipping & Returns page for estimated transit times.

Add to room temperature drinks or food
Comes with traditional Japanese wild cherry tree bark storage box, the "Kiseki"
Easy to integrate into your routine
ISO22000 standard, the highest in food quality control
Made from concentrated & defatted Japanese wheat germ extract
Each serving provides 1mg plant-derived spermidine

"Kiseki", A 250-Year Old Miracle Of Nature

For thousands of years, the Japanese have revered the Sakura (cherry tree), for its regenerative abilities, natural anti-microbial properties, and profound beauty. An ideal medium for storing anything delicate, samurai families began to use its bark over 250 years ago to craft artisanal tea caddies for storing tea and medicine. So, what better way to preserve Primeadine than your very own tea caddy? 

Japan Wheat Oxford Healthspan

What is Spermidine?

Spermidine is a powerful, naturally-occurring molecule that targets the root causes of aging, including stem cell and mitochondrial dysfunction, gut dysbiosis, inflammation, and telomere shortening.

It also induces autophagy, your body’s cellular "clean up" and recycling process that is vital to keeping you healthy.


Read Our Reviews

Recommended By Experts

Dr. Stephanie Estima


Women’s Health Expert & Author of “The Betty Body”

My hair was starting to go from gray back to […] dark brown. It was gray, and now it’s back to its original color. When I think about spermidine as a whole, the way I am viewing it is as a way to reduce systemic inflammation.

Carol Vorderman


British TV personality & Biohacker

I’m nearly 62, and I started looking into lowering my biological age. Primeadine supplements really help with, fundamentally, what’s called autophagy, which is getting rid of rubbish in your cells and using it for energy and for cell renewal and for your brain as well. Lots of you ask about what I take and this is a key essential.

Dr. Sandra Kaufmann


"Best in Medicine" Longevity Doctor & Author of The Kaufmann Protocol: Why We Age and How to Stop It

There is no question that spermidine is a crucial component to any longevity program. Thankfully, Oxford Healthspan offers an unparalleled product line. The quality is unprecedented, derived from naturally-sourced materials and manufactured in Japan. As a result, the products contain not only spermidine, but related polyamines which provide additional health benefits. As a result, I highly recommend this product line to all of my patients.

Magdalena Groselj


Biohacker & Anti-Aging Entrepreneur

I’ve noticed (via the Oura ring app) my deep and REM sleep improved enormously! My nails are so firm and my skin is even more beautiful and glowing. If you want to improve your health and rejuvenate your body, I suggest following an anti-aging protocol with Primeadine.

Luke Storey


Writer, Meditation & Metaphysics Teacher & Lifestyle Design Expert

The best spermidine supplement on the market.

Nadine Artemis


Beauty Philosophist, Author & Founder of Living Libations

My renegade beauty secret for deeper sleep, stronger nails, longer lashes, fuller hair, smoother skin, and fading freckles.

Nathalie Niddam | Oxford Healthspan

Nathalie Niddam


Certified Holistic Health Coach & Biohacker

Primeadine upregulates autophagy and mitophagy, helps the immune system to rejuvenate plus it protects DNA and supports deep sleep, hair skin, and nails. It’s a staple in my supplement stack!

The top longevity supplement for gray hair, hair loss, and anti-aging. I've been taking this for two months and I've already noticed less hair shedding. Eyelashes look longer and stronger, my skin is brighter and I'm getting much more deep sleep.

Zora Benhamou


Gerontologist, Biohacker & Sports Nutrition Coach

I’ve been taking Primeadine spermidine on and off for about 3 years. Every time I go on it, my sleep or recovery scores on my tracking devices go up. And when I go off of it, after several weeks they start to drop.

When can I Expect Results?

1-4 weeks

If you have a wearable sleep tracking device, check if there are any changes to your sleep within your first week of taking Primeadine. If not, try taking it right before bed! After at least 2 weeks, you may notice you need to clip your nails sooner than expected. This is a sign of increased cell turnover. This cellular renewal will also be happening in your hair and skin.

4-12 weeks

Changes to your hair may be noticeable after 6-8 weeks (around the time you get your hair cut next). The human clinical trial done on food-derived spermidine found improvements to cognition within 12 weeks.

Primeadine® Original Spermidine Powder Luxury Starter Kit

12+ weeks:

We recommend taking Primeadine continuously to experience the full range of benefits from enhanced cellular renewal and targeting the root causes of aging.

How To Use

Step 1: Decant the powder

First things first, decant the powder into your "Kiseki" storage box. Please remember that a little like magic fairy dust, Primeadine® powder is very fine in
texture. Open the pouch carefully and scoop it out slowly.

Step 2: Enjoy with food or liquids

Add 1g (approx. 1/2 a level teaspoon) to any food or drink below 104F (40C), such as smoothies, shakes, or porridge. When adding to liquid, we recommend using a matcha whisk or milk frother to ensure the texture is super smooth.

Step 3: When to take

We suggest taking Primeadine® Original powder with your last meal, to kickstart the autophagy experienced during your overnight fast, or with your breakfast to extend its benefits.


Have a question? Curious to learn more? The answers to our most commonly asked questions are below.

Our customer support team is available from 9:30am-5:30pm UK time.Average answer time: 24h
Contact us