If you’re searching for autophagy supplements, there’s no doubt that you know just what autophagy (pronounced “aw-TAW-fuh-gee”) is. But just in case you don’t, here’s a simple reminder: it is our body’s way of recycling its own rubbish.
Since it is a vital bodily process and has many benefits for our bodies and minds, we should do whatever we can to induce autophagy naturally.
For those of us who are familiar with this process of cellular renewal, we know that there are various ways in which we can induce autophagy through lifestyle interventions such as implementing the ketogenic diet, doing high intensity exercise and getting deep and restorative sleep. We also know that there are other, more advanced techniques that can be implemented less regularly but that bring the autophagy benefits that we desire, such as intermittent fasting, hyperbaric oxygen chambers and hot and cold therapy.
However, those of us who have tried both these interventions and techniques will know that they are difficult to implement and sustain when we are busy living our lives. So that begs the question: Are there such things as autophagy supplements that will help our bodies to induce autophagy without fasting? If there are, do they really work and are they truly hassle-free?
Autophagy Supplements and Foods of the Past
In the past, there are a number of autophagy foods and supplements that have been said to induce autophagy without fasting. These foods include:
- Green tea
- Mushrooms like chaga and reishi
While some of these proposed autophagy foods and supplements have research behind them, others do not. So in order to have your best chances of inducing autophagy, it is worth considering some of the autophagy supplements that are emerging from world-class science.
Autophagy Supplements and Foods of the Future
One of the supplements that increases autophagy, yet that has received little attention in the public sphere despite being increasingly studied by world-leading scientists, is spermidine.
Named after the source in which it was first discovered (hint: sperm), spermidine is one of a family of molecules known as polyamines. It is one of the most studied polyamines to date and has been proven to induce autophagy.
It can be found in many foods such as aged cheeses as well as wheatgerm. However, our modern lifestyle which depends heavily on processed foods, makes it difficult to make these a regular part of our diet and at the correct amount.
If we had to incorporate one spermidine-rich food into our diet on a daily basis, we would do what the long-lived Okinawans do and eat their local version of natto, a Japanese delicacy and a long-fermented tofu that has the highest spermidine content by weight. This powerful longevity enhancing superfood is fermented for 1 year in limestone caves. (That’s a Japanese anti-aging secret right there!)
Unfortunately, not only is it difficult to make and hard to find, but it has a unique smell, texture and taste that can put off even the hardiest of longevity enthusiasts.
So in reality, how many of us are in a position to easily purchase and consume natto?
The answer is: very few of us.
Spermidine Supplements and Autophagy
This is where spermidine supplements enters the picture. And not just any old spermidine supplement, but our premium, food-derived spermidine supplement, Primeadine®. It's our very own, custom-made solution for those of us who want to promote autophagy without having to fast or implement other labor-intensive lifestyle interventions, as well as for those of us who already do those things but want to further support autophagy in our cells.
Our premium spermidine supplement is carefully extracted in Japan using a precisely controlled drying method. It is then tested once in Japan and again third party tested for purity and heavy metals in the United States before being encapsulated in our Good Manufacturing Practices (GMP) certified plant in the US using vegan capsules.
Each bottle contains a one month supply, which works out at three capsules daily, our suggested daily dose.
Autophagy Explained: A Recap
For those of you who haven't much knowledge of the fascinating cellular renewal process that is autophagy, here is a little recap.
A leading Oxford University scientist, Professor Katja Simon, who studies autophagy describes it as:
“the recycling van that delivers the rubbish to the recycling centre. It is very important to degrade toxic waste for the survival of the cell, and a cell without autophagy cannot survive.” In short, the process of autophagy involves our bodies clearing out damaged cells and regenerating new ones."
Ground-breaking science by Simon and others has made it clear that autophagy is a crucial process that benefits the body at the cellular level which has a profound impact across the entire body
It is no surprise, then, that Yoshinori Ohsumi, the Japanese scientist who discovered autophagy’s mechanism of action, won the Nobel Prize in Medicine or Physiology for his work. He was able to demonstrate that this process of cellular recycling and renewal plays a key role in human health and preventing the diseases of aging, such as heart disease, Alzheimer's and poor immunity.[I think he showed the mechanism of action of autophagy, not specifically the benefits for each of these diseases, but I could be wrong] Therefore, autophagy benefits the body in many ways and, crucially, can slow the ageing process if we combat decreasing autophagy levels.
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