Primeadine® Original Spermidine Supplement 6-Bottle Bundle - Hand Held

My only supplement I could not live without

It is the only supplement that makes me sleep, look and feel better. The company is first class as well. I have been a long time supporter and will never stop.

— Tim K.

Primeadine Original and Gluten Free with glass of water

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Slow Aging With Primeadine® Spermidine

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Slow Aging With Primeadine® Spermidine

Primeadine® works on a cellular level to "spring clean" old cells and make way for new, healthy ones. Resulting benefits include hair regrowth and gray hair reversal, radiant skin, and more stamina in the bedroom...

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"My Eyelashes and Eyebrows are Growing Thicker"

“Primeadine is the only longevity supplement that supports 9 of the 12 hallmarks of aging. Even better, they have the only gluten-free version of spermidine. I take this morning and evening and my hair color is returning, my eye sight is improved and my eye lashes and eyebrows are growing thicker. These are only the external manifestations of this powerful anti-aging supplement. Oxford Health Span is a QUALITY company too.”

— Susan Bratton, Sexual Biohacker

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Loved By Thousands Of Customers

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Primeadine®'s Unique Longevity Benefits

Healthy Heart Cells & Sexual Vibrancy

Ever thought about how your heart health impacts your performance in the bedroom? Primeadine spermidine rejuvenates heart cells and promotes blood flow, meaning you'll be in much better stead for physical activity of all kinds... It also increases testosterone levels in men, making it a multi-pronged approach guaranteed to upgrade your sex life and overall health and wellbeing!

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Banish Stray Grays & Bring On Hair Growth

Better cell renewal is a fast-track ticket to new hair growth, glowing, vital skin and stronger, healthier nails. To top it all off, spermidine moves hair follicles from the shedding phase to the growth phase and keeps them there for longer. And get this, it's during this growth phase that hair color pigment is produced, which is why many Primeadine clients experience gray hair reversal along with their new, luscious locks!

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Oxford Healthspan Affiliate Program

Balance Hormones & Promote Healthy Ovaries

Scientifically proven to lower cortisol, the stress hormone, while boosting vital hormones associated with youthfulness, fertility, and vitality, such as progesterone, estradiol, DHEA, and pregnenolone in women, and testosterone in men, spermidine is an essential tool for balancing hormones. Recent research has even hailed it as groundbreaking in fertility for its ability to improve egg quality in aged mice by stimulating autophagy.

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Recommended By Longevity Experts

Dr. Olivia Lesslar


Medical Doctor with a Special Interest in Longevity & Complex Conditions

Primeadine is an exceptional quality spermidine that I use in many protocols, especially when I am trying to induce autophagy. These include such diverse protocols as those for tinnitus, post-viral syndromes, 'autoimmunity', and graying hair! I am especially pleased to have a gluten-free version to offer patients. 

Nadine Artemis


Beauty Philosophist, Author & Founder of Living Libations

My renegade beauty secret for deeper sleep, stronger nails, longer lashes, fuller hair, smoother skin, and fading freckles.

Dr. Sandra Kaufmann


Longevity Doctor & Author of The Kaufmann Protocol: Why We Age and How to Stop It

There is no question that spermidine is a crucial component to any longevity program. Thankfully, Oxford Healthspan offers an unparalleled product line. The quality is unprecedented, derived from naturally-sourced materials and manufactured in Japan. As a result, the products contain not only spermidine, but related polyamines which provide additional health benefits. As a result, I highly recommend this product line to all of my patients.

Carol Vorderman


British TV personality & Biohacker

I’m nearly 62, and I started looking into lowering my biological age. Primeadine supplements really help with, fundamentally, what’s called autophagy, which is getting rid of rubbish in your cells and using it for energy and for cell renewal and for your brain as well. Lots of you ask about what I take and this is a key essential.

Luke Storey


Writer, Meditation & Metaphysics Teacher & Lifestyle Design Expert

The best spermidine supplement on the market.

Magdalena Groselj


Biohacker & Anti-Aging Entrepreneur

I’ve noticed (via the Oura ring app) my deep and REM sleep improved enormously! My nails are so firm and my skin is even more beautiful and glowing. If you want to improve your health and rejuvenate your body, I suggest following an anti-aging protocol with Primeadine.

Dr. Stephanie Estima


Women’s Health Expert & Author of “The Betty Body”

My hair was starting to go from gray back to […] dark brown. It was gray, and now it’s back to its original color. When I think about spermidine as a whole, the way I am viewing it is as a way to reduce systemic inflammation.

Zora Benhamou


Gerontologist, Biohacker & Sports Nutrition Coach

I’ve been taking Primeadine spermidine on and off for about 3 years. Every time I go on it, my sleep or recovery scores on my tracking devices go up. And when I go off of it, after several weeks they start to drop.

Nathalie Niddam | Oxford Healthspan

Nathalie Niddam


Certified Holistic Health Coach & Biohacker

Primeadine upregulates autophagy and mitophagy, helps the immune system to rejuvenate plus it protects DNA and supports deep sleep, hair skin, and nails. It’s a staple in my supplement stack!

One of my non-negotiable supplements for better skin, hair, lash growth, and autophagy. And best of all - improved sleep.

Dr. Olli Sovijarvi


Pioneer of Holistic & Preventive Medicine in Finland & Medical Doctor & CEO of Biohacking Center

My wife has been taking it for six months and I think she looks younger and her hair growth has come back after pregnancy, and nails, and all kinds of things that are a reflection of good vitality.

The top longevity supplement for gray hair, hair loss, and anti-aging. I've been taking this for two months and I've already noticed less hair shedding. Eyelashes look longer and stronger, my skin is brighter and I'm getting much more deep sleep.What I noticed is: incredibly thick and fast-growing eyelashes, hair, and nails; improved skin texture; constant energy levels; great digestion; stronger immunity; deep, restful sleep; balanced hormones and regular menstruation.

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Oxford University Oxford Healthspan

World-Class Science

It was at the University of Oxford that a scientist, autophagy expert and now one of our scientific advisors, Katja Simon, introduced our Founder, Leslie Kenny, to spermidine, and Oxford Healthspan was born. Meet our scientific and clinical board of advisors and learn more about the Nobel Prize-winning science behind spermidine below.

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Leslie Kenny Oxford Healthspan Founder

About Our Founder

When Leslie was 37 she was diagnosed with a trio of autoimmune diseases - lupus, rheumatoid arthritis, and Hashimoto's Thyroiditis - and told she had five years to live. Now, at age 58, she is autoimmune disease-free, has no gray hairs, and is the biological age of 21! Find out more about her health journey below.

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