Getting started with Primeadine® Spermidine Supplements

You've received your Primeadine® spermidine supplement... what now?

Here are the answers to the most common questions we get from our customers (with a few extra ones for good measure), so that you can maximize the benefits of taking Primeadine® from Day 1.

Where should I store my bottles?

Please store your bottles in a cool, dry place, away from direct sunlight. If you live in a very hot climate, please store the bottles in the refrigerator.

What is the best time to take spermidine?

There is no "right" time to take spermidine, and our clients (and the whole team!) take it at different times of the day. We suggest taking the capsules with your last meal of the day, or just before bed on an empty stomach. 

Can I add it to my coffee or tea?

No. Primeadine® should not be added to hot liquids, as this will reduce its potency.

Can I add it to my smoothie?

Yes! Feel free to add it to any cold or room-temperature beverages. 

Can I take it while fasting?

Absolutely! Please do not exceed 6mg per day (18 capsules) - see next question. 

Can I double/triple/quadruple my dosage?

While Primeadine® is a botanical compound, found in the food supply and also made in our bodies, please consult your practitioner if you would like to consume more than the daily recommended dosage of 1mg. There are no FDA guidelines regarding spermidine consumption, but the European Food Safety Agency has stated that dosages of up to 6mg of spermidine from concentrated wheat germ are considered safe in humans.

How should I split the capsules during the day, if at all? 

You can split your dosage if you would like: 1 at each meal, 3 at dinner, or 1 at lunch and 2 at dinner.

Should I take my spermidine supplements with a meal, or on an empty stomach? 

We suggest you start taking Primeadine® with a meal, and then, if you would like, you can take it on an empty stomach in the morning or before bed to help amplify the positive effects of fasting.

What should I feel when taking Primeadine® for the first time? 

Primeadine® works at a cellular level, so you won't feel any "fireworks" the first time you take it. That said, some of our customers have reported deeper sleep, as measured by the ōura ring, when taken at night. See our Reviews section for more! 

Do you have another question you'd like us to answer? Tell us in the comments section and we'll add it to the article!