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Deregulated Nutrient Sensing: Hallmark of Aging #5
There are many cues to tell us when we are hungry – it could be the growling and gurgling of the belly, feeling low energy, or even the ring of the lunch bell. On a cellular level, hunger is, in pa...
Gut Dysbiosis: Hallmark of Aging #12
Bacterial diversity in the gut is established during childhood and remains relatively stable into adulthood. But, the architecture and activity of the bacteria undergoes gradual changes during agi...
Inflammation & "Inflammaging": Hallmark of Aging #11
Inflammation is a recognizable accompaniment to aging. Demonstrably, over one in four American adults between the ages 45 and 64 and nearly half of all Americans over 65 have been diagnosed with o...
Disabled Macroautophagy: Hallmark of Aging #10
Macroautophagy is one type of autophagy and involves the containment of cytoplasmic material into vesicles, whose contents are later digested or broken down into parts by lysosomes, another cellula...
Altered Intracellular Communication: Hallmark of Aging #9
As people (and their cells) age, the communication between their cells change. Although the cells aren’t deciding not to communicate, the communication becomes deregulated particularly as inflammat...
Stem Cell Exhaustion: Hallmark of Aging #8
The latest anti-aging skincare product might promise to repair, renew, and rejuvenate, however, they don’t promise to regrow. Only your stem cells can do that; but this is actually what you need most.