The Science & Art of Aging Well

Inflammation & "Inflammaging": Hallmark of Aging #11

Inflammation is a recognizable accompaniment to aging. Demonstrably, over one in four American adults between the ages 45 and 64 and nearly half of all Americans over 65 have been diagnosed with o...

Autophagy Benefits for Skin Radiance & Renewal

I don’t need to tell you that there are several industries focused on selling you things to improve your skin or at least to look younger and better. From skin care and makeup, cosmetic surgeries a...

Spermidine in the Body: Where It Comes From and How to Nourish Your Levels

Anton van Leeuwenhoek, the microscopy pioneer, described crystals in human semen in 1678, and named them spermine and spermidine. A few hundred years later, these crystals, now called polyamines, a...

Disabled Macroautophagy: Hallmark of Aging #10

Macroautophagy is one type of autophagy and involves the containment of cytoplasmic material into vesicles, whose contents are later digested or broken down into parts by lysosomes, another cellula...

Altered Intercellular Communication: Hallmark of Aging #9

As people (and their cells) age, the communication between their cells change. Although the cells aren’t deciding not to communicate, the communication becomes deregulated particularly as inflammat...